Water plays an important role in the paper manufacturing process. It help fibers to flow from the apparatus which then de-fibers the wood pulp down to the manufacturing wire. The flow of water can be recycled due to technological developments. The remaining waste such as bacteria, fungi, yeast, and algae in pipes and tanks gives rise to a viscous deposit commonly known as “slime.” Slime causes issues such as soiling and breakage of continuous sheet of paper. In many cases, slime results in delay in the paper manufacturing process, thereby causing economic losses. Decrease in water consumption, increase in usage of secondary fibers & surface water, rise in usage of higher levels of filler, increase in chemical addition, faster running machines, and manufacturing under alkaline and neutral conditions have augmented the problems of deposit formulation in the paper manufacturing process. Various biocidal agents such as sodium chlorophenate, phenates, and mercurial compounds are used to control slime. These controlling agents provide temporary control over slime formulation. Biocidal agents have started resulted in water pollution, which is a major environmental concern. Based on...